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心肌梗死后缝隙连接和缓慢传导以及室性心动
SaffitzJE,KléberAG.GapJunctions,SlowConduction,andVentricularTachycardiaAfterMyocardial[J].JournaloftheAmericanCollegeofCardiology,,60(12):-.
Abstract：
EDITORIALCOMMENT
1.theyhaveallconvergedontheideathatgapjunctionremodelingcanreduceintercellularcouplingandtherebyslowconductioninwaysthatcontributeimportantlytothepathogenesisofre-entrantVTaftermyocardialinfarction.
2.Recognitionofthisconcepthasalsoraisedtheobviouspossibilitythatpreservationorenhancementofintercellularcouplinginthe
infarctborderzonemightdecreasetheriskforre-entrantVT.
3.concludethatincreasedexpressionofCx43inhealedinfarctborderzonesissuf?cienttoreducearrhythmiasusceptibilityandtheysuggestfurtherthattargetedCx43genetransfermightbeaviablefuturetherapyinpatientswithpost-infarctionVT.
4.Precisegeneticinterventionsinalargeanimalmodelwouldbeofgreatpotentialvalue,therefore,inelucidatingtheroleofspeci?cmoleculesinVTaftermyocardialinfarction
5.Potentialclinicalapplicationsofso-calledantiarrhythmicpeptidesorother复方川芎酊白癜风的饮食医疗问题和影响
